Children's Hospital of Philadelphia

Recently, our Critical Care Medicine experts hosted the Beatrice Nicoletti & CHOP Resuscitation Science Center Conference at our Hub for Clinical Collaboration. The conference highlighted the global impact of our Resuscitation Science Center and Division of Critical Care Medicine, bringing together more than 130 experts from around the world. Attendees included pediatric physicians, nurses, paramedics, and research scientists to advance resuscitation science and improve outcomes for children. Learn more about our Resuscitation Science Center: http://ms.spr.ly/6042vBCXm.

Proud to share this recogntion from the Philadelphia Business Journal!

Children’s Hospital of Philadelphia was proud to be part of the Breakthrough Prize Foundation awards this weekend—often called the “Oscars of Science”—with our work featured as examples of the transformative power of gene therapy. From pioneering the first FDA-approved gene therapy for inherited blindness to advancing first-of-its-kind personalized gene editing, CHOP and Penn Medicine, University of Pennsylvania Health System teams were recognized on a global stage. Drs. Katherine A. High, Jean Bennett, and Albert M. Maguire—whose groundbreaking research restored sight for patients with rare genetic blindness—were awarded the Breakthrough Prize in Life Sciences. Equally powerful were the voices of patients and families—like Hannah, who shared how gene therapy allowed her to see the world in a whole new way, and KJ, whose story represents the future of personalized medicine through the work of Rebecca Ahrens-Nicklas and Kiran Musunuru. Moments like these are a reminder: behind every breakthrough is a child, a family, and a future changed. Read more and see highlights from the evening: http://ms.spr.ly/6042v8GQI The full award show will premiere on YouTube on Sunday, April 26th at 3PM Eastern / 12PM Pacific.

Join us virtually on Thursday for our next Synovial Sarcoma Foundation Tumor Board hosted by CHOP, Penn Medicine, University of Pennsylvania Health System, and Spence Family Synovial Sarcoma Foundation. 🩺 The multidisciplinary forum brings together medical professionals from around the world to discuss complex synovial sarcoma cases in both children and adults. To join the Tumor Board or refer a case, please email SynovialSarcomaRegistry@chop.edu. #SynovialSarcoma #SarcomaCare #RareCancer #PatientAdvocacy

We are thrilled to congratulate our CHOP and Penn Medicine, University of Pennsylvania Health System team – Drs. Katherine High, Albert Maguire and Jean Bennett – on receiving the Breakthrough Prize in Life Sciences for their work in developing the first FDA-approved gene therapy for an inherited condition, which dramatically improves sight in people with a form of blindness called Leber Congenital Amaurosis (LCA). Their story is a masterclass in scientific resilience. At a time when gene therapy faced immense skepticism, this team stayed the course. Their breakthrough treatment for LCA did more than restore sight; it provided a regulatory and scientific roadmap for the entire field of genomic medicine.

Drs. David Hill and Lisa Young were recently recognized with the International Klosterfrau Group Award for Research of Airway Diseases in Childhood, a prestigious international honor presented annually at the German Society for Pediatric Pneumology meeting. The award highlights their study showing that certain lipids – fats commonly found in obesity-related foods – can trigger asthma-like inflammation in the lungs. Study findings suggest that existing medications could potentially be repurposed to treat this form of asthma when paired with dietary changes. Read the full study here: https://lnkd.in/e8w8VAfA.

New research published in Pediatric Critical Care Medicine found that a tele‑simulation program for pediatric emergency staff at Komfo Anokye Teaching Hospital in Kumasi, Ghana was associated with a large decrease in inpatient hospital deaths among children with suspected sepsis. In many low-resource settings, access to consistent, hands-on emergency training is limited. This culturally adapted, cost-effective program was designed to help frontline clinicians better recognize and treat pediatric sepsis – demonstrating the potential of scalable solutions to improve outcomes globally. Read more: http://ms.spr.ly/6042Qh9XM.

Join us in congratulating Dr. John Maris, Professor of Pediatrics in our Cancer Center, on receiving the 2026 National Cancer Institute (NCI) Alfred G. Knudson Award for Research Excellence in Cancer Genetics. Named in honor of Dr. Alfred G. Knudson, a physician and geneticist whose work transformed our understanding of cancer biology, this prestigious award recognizes individuals who have made groundbreaking contributions to cancer genetics research. Dr. Maris was selected by the NCI Director and invited to deliver a keynote lecture at the NCI Annual Intramural Scientific Retreat held last month at Hood College. We are proud to celebrate Dr. Maris’s continued leadership and impact in advancing discoveries that bring us closer to better outcomes for children with cancer.

We’re excited to announce a strategic collaboration with Labcorp to accelerate the discovery, development and nationwide availability of specialized pediatric diagnostics. All children deserve access to diagnostics built for them. Combining our clinical and research expertise with Labcorp’s national reach will accelerate development, validation, and scaling of pediatric diagnostics in oncology, genetics, immune disorders, and rare disease. Learn more: http://ms.spr.ly/6045QhgFJ.

During #NationalVolunteerMonth, help us celebrate the CHOP employees who bring the Healthy Kids Running Series (HKRS) to life! 👟 Since 2014, CHOP employee volunteers have powered the West Philadelphia series, and thanks to their incredible impact, HKRS expanded to the Norristown community in 2023. Each location hosts two five-week sessions, one in the spring and one in the fall. Learn more about the running series: http://ms.spr.ly/6044Qh9Og.